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In another study, this time in obese mice, cardarine reduced the risk of heart disease by lowering ldl cholesterol, triglycerides,. The clinical presentation of myocarditis can vary from insidious self-limiting chest pain to overt heart failure, cardiogenic shock,. Cardarine may reduce the risk of plaque build-up in the arteries of the heart (atherosclerosis) by relaxing/widening the blood. Limited exercise capacity can result from multiple abnormalities in heart failure, which include changes in intramuscular metabolism (20, 21, 28, 46),. Cardarine increased the growth of new blood vessels in human heart cells (increasing vegf). This could be beneficial for those with heart. This discovery led the researchers to see if cardarine could be used to reduce the risk of heart disease as well as its complications. Objective the development of heart failure is invariably associated with extensive fibrosis. 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